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[ Source: r-bioc-pfamanalyzer  ]

Пакунок: r-bioc-pfamanalyzer (1.6.0+dfsg-1)

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Warning: This package is from the experimental distribution. That means it is likely unstable or buggy, and it may even cause data loss. Please be sure to consult the changelog and other possible documentation before using it.

GNU R identification of domain isotypes in pfam data

Protein domains is one of the most import annoation of proteins that are with the Pfam database/tool being (by far) the most used tool. This R package enables the user to read the pfam prediction from both webserver and stand-alone runs into R. It was recently shown most human protein domains exist as multiple distinct variants termed domain isotypes. Different domain isotypes are used in a cell, tissue, and disease- specific manner. Accordingly, it was found that domain isotypes, compared to each other, modulate, or abolish the functionality of a protein domain. This R package enables the identification and classification of such domain isotypes from Pfam data.

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